INTRODUCTION

Oxalyl chloride is a colorless liquid with pungent odor. The chloride is volatile and moisture sensitive. As a useful reagent employed in a variety of chemical syntheses, it finds applications in APIs, intermediates, and agrochemicals.

Manufacture

The acid chloride is produced by chlorination of oxalic acid by using phosphorous pentachloride.

SynonymsEthanedioyl dichloride
Oxalic acid dichloride
CAS no.79-37-8
EINECS no.201-200-2
Molecular formulaC2Cl2O2
Molecular weight126.93
Structure

Pharmaceutical Applications

Oxalyl chloride is a KRM to produce the following APIs:

Tivantinibanti-cancer drug
Diclofenacanti-inflammatory drug

Agrochemicals Applications

The acid chloride is also a raw material in manufacture of many plant protection products such as:

Chinomethionat
Triflumuron
Metsulfuron
Bensulfuron-Methyl
Pyrimidine-sulfuron

Other Vital Applications

as catalyst in production of ketones and aldehydes from alcohols
as chlorinating agent to make acid chlorides from acids
as a reagent to convert aromatic products into corresponding acids
in manufacture of dioxane tetra-ketone and 2,3-dichloroquinoxaline-6-carbonyl chloride

SPECIFICATIONS

TestUnitSpecification
AppearanceClear colorless to pale yellow liquid
Purity by GC%Min 99.0

STORAGE
The product is stored at ambient temperature.

PACKING
250 kg UN approved steel drum

ExSyn offers oxalyl chloride on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.

More Products
In focus: Colchicine
Products in focus · 09/09/2025

Colchicine is a naturally occurring alkaloid obtained primarily from the autumn crocus (Colchicum autumnale) and related species. It has been used in medicine for centuries, especially for the treatment of gout and Familial Mediterranean Fever. In modern medicine, Colchicine is valued also in conditions like pericarditis, Behçet’s disease, and certain dermatological and cardiac disorders.

READ MORE
In focus: 1-Butylimidazole
Products in focus · 02/09/2025

1-Butylimidazole is a versatile organic heterocyclic compound belonging to the imidazole family, where a butyl group (–CH₂–CH₂–CH₂–CH₃) is attached to the nitrogen atom at the 1-position of the imidazole ring. Its applications span organic synthesis, materials science, and bioactive compound development due to its tunable physicochemical properties and structural versatility.

READ MORE
In focus: Atropine Sulfate, monohydrate
Products in focus · 26/08/2025

Atropine sulfate monohydrate is a chemical compound, specifically a salt of atropine and sulfuric acid, with one water molecule (monohydrate) attached. It is commonly used as a medication and in research due to its anticholinergic properties, meaning it blocks the effects of acetylcholine at muscarinic receptors.

READ MORE
In focus: 4-Aminobenzoic Acid (PABA)
Products in focus · 19/08/2025

4-Aminobenzoic acid, commonly abbreviated as PABA, is an aromatic amine and carboxylic acid compound. It consists of a benzene ring substituted with an amino group (–NH₂) in the para position to a carboxylic acid group (–COOH).

READ MORE
In focus: 2-Amino-5-Nitrophenol
Products in focus · 12/08/2025

2-Amino-5-Nitrophenol (5-NAP) is an organic compound with the molecular formula C₆H₆N₂O₃. It is a substituted phenol with both an amino group (-NH₂) and a nitro group (-NO₂) attached to a benzene ring, along with a hydroxyl group (-OH).

READ MORE
In focus: Pongamol Extract
Products in focus · 05/08/2025

Pongamol is a naturally occurring flavonoid primarily extracted from the seeds and leaves of the Pongamia pinnata tree (also known as Karanja tree), native to South and Southeast Asia. It is a cream-colored compound that belongs to the flavonoid family and is known for its antioxidant, anti-inflammatory, antimicrobial, and pesticidal properties. It is one of the key bioactive constituents of Pongamia oil.

READ MORE
In focus: Biobased Ethyl Acetate
Products in focus · 29/07/2025

Biobased Ethyl Acetate is an environmentally friendly solvent made from renewable sources like bioethanol extracted from sugarcane, corn, and other forms of biomass. Unlike traditional ethyl acetate, which is typically derived from fossil fuels, this green alternative shares the same chemical structure (C₄H₈O₂) and functional performance—offering comparable versatility with a significantly lower environmental footprint.

READ MORE
In focus: Palmitoyl Chloride
Products in focus · 22/07/2025

Palmitoyl chloride is a long-chain fatty acid derivative. It is the acid chloride form of palmitic acid; a saturated fatty acid commonly found in palm oil and other natural fats. It appears as a colorless to pale yellow liquid with a sharp odour and is highly reactive, especially toward water, alcohols, and amines.

READ MORE
In focus: Lycopene
Products in focus · 15/07/2025

Fungal Lycopene is an acyclic carotene belonging to a large group of naturally-occurring pigments known as carotenoids. It contains at least 90% of all-trans-lycopene and minor quantities of 13-cis-lycopene and β- and γ-carotene. It is used as an intermediate in the biosynthetic pathway of β-carotene. Its role in the pharmaceutical and food industries stems from its demonstrated health benefits—such as anticancer and cardiovascular protection—alongside its widespread use as a natural food colorant.

READ MORE