Octenidine dihydrochloride is a cationic surfactant, with a gemini-surfactant structure. Since 1987, it has been used primarily in Europe as an antiseptic prior to medical procedures, including on neonates. It is safe to handle and chemically stable.


This quaternary compound salt is derived from octenidine and hydrochloric acid.

CAS no.70775-75-6
EINECS no.274-861-8
Molecular formulaC36H64Cl2N4
Molecular weight623.83


Octenidine dihydrochloride finds extensive application in medical, industrial, and even food and cosmetic realms
Widely recognized for its exceptional antiseptic, antibacterial, and antifungal properties, It is used for the treatment of wound infections and for disinfecting the skin and mucous membrane.
Also, it exhibits anti-inflammatory and analgesic properties, providing relief from inflammation and pain.
Octenidine dihydrochloride has been subject to extensive in vitro studies. Its efficacy in treating bacterial and fungal infections has been explored, showcasing its effectiveness against both gram-positive and gram-negative bacteria.
Researchers have evaluated its potential as a combatant against viruses, revealing its favorable outcomes in combating select viral strains.


DescriptionA white to off white powder
SolubilityFreely soluble in Methanol and Dichloromethane, slightly soluble in N,N‐dimethyl formamide
a. By IR spectruma. The IR spectrum of sample should be concordant with that of working standard of Octenidine Dihydrochloride
b. Chlorideb. It gives reaction for chloride
Assay by HPLC%Between 98.0 to 101.0 on anhydrous basis
Related substances by HPLC
a. 4-Octyl amino pyridine%NMT 0.15
b. Single unknown impurity%NMT 0.10
c. Total impurities%NMT 0.5
Heavy metalsppmNMT 10.0
Sulphated ash%NMT 0.5
Water content%NMT 2.0
Residual solvents
MethanolppmNMT 3000
N,N-Dimethyl formamideppmNMT 880
AcetoneppmNMT 5000


25 kg Fiber drum.


Keep containers tightly closed in a dry, cool and well-ventilated place. Store at room temperature.



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