Nicotinamide riboside chloride (NRCL) is a unique form of vitamin B3. As a precursor to nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme involved in various cellular processes, it has sparked interest in the realms of aging, metabolism, and overall cellular health.


It is synthesized by reacting nicotinamide and ribose in a controlled environment to obtain nicotinamide riboside which is subsequently converted to its chloride form by reacting it with hydrochloric acid.

Synonym3-(aminocarbonyl)-1-β-D-ribofuranosyl-pyridinium, monochloride
CAS no.23111-00-4
EINECS no.807-820-5
Molecular formulaC11H15ClN2O5
Molecular weight290.7
It is a form of vitamin B3 (Niacin) and is marketed as a dietary supplement
It is being explored for its potential therapeutic applications in pharmaceuticals, including the treatment of metabolic disorders and neuro degenerative diseases
It may also find applications in the cosmetics industry for its potential anti-aging properties and skin health benefits
It is used as a research tool in scientific studies investigating its effects on metabolism, aging, and various health conditions


AppearanceWhite to off-white powder
Identification by HPLCThe retention time should match with the standard
Purity%≥ 99.0
Nicotinamide%≤ 1.0
Single unidentified impurity%≤ 0.5
Heavy Metalsppm≤ 20
Residue on ignition%≤ 0.5
Ethanolppm≤ 5000
Methanolppm≤ 1000
ACNppm≤ 100
Water content%≤ 1.0
Loss on drying%≤ 0.5
Aerobic bacterial countCFU/g≤ 750
E. ColiMPN/g≤ 30


Store in dry, dark place at temperature between 2 – 8°C, avoid direct sunlight


HDPE drums

REACH Status

Not registered

ExSyn offers Nicotinamide Riboside Chloride (NRCL) on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

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