INTRODUCTION
Dichloroacetyl chloride, acronymed DCAC, is an organic solvent that belongs to the category of acid chlorides. Its uses include manufacture of APIs, agrochemicals, and a series of intermediates. It is also applied in synthesis of biologically active compounds.
Manufacture
It is commercially manufactured by chlorination of dichloroacetic acid with chlorosulphonic acid.
Synonym | DCAC alpha,alpha-Dichloroacetyl chloride |
CAS no. | 79-36-7 |
EINECS no | 201-199-9 |
Molecular formula | C2HCl3O |
Molecular weight | 147.39 |
Structure |
Applications
API – DCAC is a KRM in manufacture of: |
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Chloramphenicol, an antibiotic |
Intermediates – The acid chloride is used in manufacture of intermediates such as: |
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4-Methyltroplone |
4’-Hydroxy-3’-methoxyacetophenone |
(RS)-3-Dichloroacetyl-5-(2-furanyl)-2,2-dimethyl-1,3-oxazolidine |
Tetrachloroacetyl chloride |
Agrochemicals – Dichloroacetyl chloride is used in production of various agrochemicals such as: |
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Tetrachlorovinphos, an insecticide |
Heptenophos, also an insecticide |
Benoxocar, a herbicide |
Flurochloridon, also a herbicide |
Others |
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In protection of oxindoles |
In synthesis of substituted benzothiazoles |
In synthesis of biologically active compounds like hormones and enzymes |
SPECIFICATIONS
Test | Unit | Specifications |
---|---|---|
Appearance | – | Colourless liquid |
Identification by IR | – | Should conform to the reference standard |
Boiling Range | °C | 107.0 – 108.0 |
Assay | % | Min 98.0 |
STORAGE
Stored at ambient temperature
PACKING
250 kg UN-approved Composite drum
REACH Status
Not registered
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