Calcium Gluconate is the calcium salt of gluconic acid, an oxidation product of glucose, and contains 9.3% calcium, which is about one-third of the calcium in the strength of calcium chloride. It is an ingredient found in a variety of supplements and vitamins and is used to lower potassium in the blood. Calcium gluconate is used as a mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia.
It is made by mixing gluconic acid with calcium carbonate or calcium hydroxide
D-Gluconic acid calcium salt
|Calcium gluconate is used to prevent or treat calcium deficiencies. Oral calcium salts are used as dietary supplemental therapy for people who may not get enough calcium in their regular diet|
|Calcium gluconate is used as a cardioprotective agent in high blood potassium|
|Calcium gluconate is the antidote for magnesium sulfate toxicity|
Calcium gluconate is also used as/for:
|Hungry Bone Syndrome|
|Tumor Lysis Syndrome|
SPECIFICATIONS – for injection, EP
|Appearance||–||White or almost white, crystalline or granular powder|
|Solubility||–||Sparingly soluble in water, freely soluble in boiling water|
B. Reaction of Calcium
Shall pass the test
Shall pass the test
|Appearance of solution||–||At 60°C, solution S is not more intensely colored than reference solution B7. After cooling to 20°C, it is not more opalescent than reference suspension II.|
|pH||–||Between 6.4 and 8.3|
|Organic impurities & Boric acid||–||Shall pass the test|
|Sucrose & reducing sugars||–||No red precipitate is formed|
|Magnesium & alkali metals||%||Max 0.4|
|Assay as C12H22CaO14H2O||%||Between 99.0 and 101.0|
|Bacterial endotoxins||IU/g||Max 167|
|Total aerobic microbial count||CFU/g||Max 10(square)|
Store in a cool & dry place. Keep away from moisture.
25 kg drum.
REGISTRATION / CERTIFICATION
US-DMF, CEP, EU-GMP, EU-WC (Written Confirmation)
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