INTRODUCTION
Acryloyl chloride is an organic liquid from the class of acid chlorides. It is a toxic and lachrymatic chemical that has a variety of applications in APIs, intermediates and polymers.
Manufacture
It is manufactured by chlorination of acrylic acid by phosphorus oxychloride.
| Synonym | 2-Propenoyl chloride Acrylic acid chloride |
| CAS # | 814-68-6 |
| EINECS # | 212-399-0 |
| Molecular formula | C3H3ClO |
| Molecular weight | 90.51 |
| Structure |  |
Applications
APIS
| Poziotinib (an anti-cancer drug) |
| Ibrutinib (also an anti-cancer drug) |
Intermediates
| 1-(2,3-Dihydro-1H-indol-1-yl)-2-propene-1-one |
| N-Isopropylacrylamide |
| N-Acryloxysuccinimide |
| 1,4-Diacryloylpiperazine |
| Dodecyl acrylate |
Polymers
| Acrylic polymers |
| Poly(styrene-acryloyl chloride)copolymer |
| Acrylate-based conducting polymers |
Others
| Used as building block to introduce acrylic group in organic compounds |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Colourless to pale yellow liquid |
| Identification by GC | – | Main peak for sample solution should correspond to that of standard solution |
| Specific gravity at 30 deg cel | – | 1.112 – 1.116 |
| Purity by GC | % | Min 98.00% |
| Acrylic acid by GC | % | Max 1.00% |
| 3-Chloropropionyl chloride by GC | % | Max 0.50% |
| Total impurities by GC | % | Max 2.00% |
| BHT as stabilizer | ppm | Max 500 |
STORAGE
Recommended storage temperature : 2° to 8°C
Shipped under temperature-controlled conditions
PACKING
100 kg UN-approved HDPE drum
REACH Status
Not registered
ExSyn offers acryloyl chloride on commercial scales at refrigerated temperature and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Benzene-d6 is a deuterated form of benzene, where hydrogen atoms are replaced by deuterium, making it ideal for use as a solvent in NMR spectroscopy. It is widely employed in chemical, pharmaceutical, and environmental research for isotopic labeling and reaction mechanism studies.
Pyridinium tribromide, an organic solid from the category of heterocyclic halides, is a highly efficient and selective bromination agent in organic syntheses. It is also used in production of APIs and intermediates.
Pyrophosphoryl Tetrachloride is a colorless fuming corrosive liquid .It consists of a pyrophosphate (a molecule with a P-O-P bond) group, where one phosphorus atom is bonded to four chlorine atoms and the other is bonded to three chlorine atoms.
It is a reactive chemical compound and should be handled with care. Commonly used in the synthesis of other phosphorus-containing compounds and as a chlorinating agent in organic chemistry
Trifluoroacetic acid (TFA) is widely used in organic synthesis as a solvent, catalyst, and reagent, owing to its reactivity and stability under adverse conditions. It is considered as one of the most economical fluorinated building blocks.
Triton X-100 is a widely used non-ionic surfactant and emulsifier that effectively solubilizes powders and proteins. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.
Chlorocresol, or 4-chloro-3-methylphenol, also known as p-chloro-m-cresol, is efficacious against various bacteria, yeast and fungi. It is a potent disinfectant and antiseptic and acts as preservative in cosmetics, medicinal, and personal care products for both humans and animals.
INTRODUCTION 2-Mercaptopyridine, a sulfur-containing heterocyclic compound, is a derivative of pyridine with a thiol functional group. This compound has garnered interest in various fields, including organic synthesis, medicinal chemistry, and materials science. MANUFACTURE It is synthesized by reacting 2-chloropyridine with thiourea in ethanol and aqueous ammonia. The mixture is heated to reflux, facilitating nucleophilic substitution […]
INTRODUCTION Glycidol is a viscous organic compound that belongs to the class of beta-oxyalcohols. Its reactivity is attributed to the epoxy moiety at beta position. The alcohol finds applications majorly in APIs, glycidyl esters and ethers, and in alkanolamines. Manufacture It is manufactured from 2-Chloro-1,3-propanediol in a catalyzed ring closure process. The unreacted reactant is […]
INTRODUCTION Ammonium dimolybdate commonly known as ADM, is an inorganic compound. It is a white, water-soluble solid and serves as an intermediate in producing molybdenum compounds from its ores. MANUFACTURE It is produced by roasting molybdenum ore to obtain its trioxide, which is then leached with ammonium hydroxide to form ammonium dimolybdate. This solution is […]