INTRODUCTION
Acryloyl chloride is an organic liquid from the class of acid chlorides. It is a toxic and lachrymatic chemical that has a variety of applications in APIs, intermediates and polymers.
Manufacture
It is manufactured by chlorination of acrylic acid by phosphorus oxychloride.
| Synonym | 2-Propenoyl chloride Acrylic acid chloride |
| CAS # | 814-68-6 |
| EINECS # | 212-399-0 |
| Molecular formula | C3H3ClO |
| Molecular weight | 90.51 |
| Structure | ![]() |
Applications
APIS
| Poziotinib (an anti-cancer drug) |
| Ibrutinib (also an anti-cancer drug) |
Intermediates
| 1-(2,3-Dihydro-1H-indol-1-yl)-2-propene-1-one |
| N-Isopropylacrylamide |
| N-Acryloxysuccinimide |
| 1,4-Diacryloylpiperazine |
| Dodecyl acrylate |
Polymers
| Acrylic polymers |
| Poly(styrene-acryloyl chloride)copolymer |
| Acrylate-based conducting polymers |
Others
| Used as building block to introduce acrylic group in organic compounds |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Colourless to pale yellow liquid |
| Identification by GC | – | Main peak for sample solution should correspond to that of standard solution |
| Specific gravity at 30 deg cel | – | 1.112 – 1.116 |
| Purity by GC | % | Min 98.00% |
| Acrylic acid by GC | % | Max 1.00% |
| 3-Chloropropionyl chloride by GC | % | Max 0.50% |
| Total impurities by GC | % | Max 2.00% |
| BHT as stabilizer | ppm | Max 500 |
STORAGE
Recommended storage temperature : 2° to 8°C
Shipped under temperature-controlled conditions
PACKING
100 kg UN-approved HDPE drum
REACH Status
Not registered
ExSyn offers acryloyl chloride on commercial scales at refrigerated temperature and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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