INTRODUCTION
1,3-Dihyrdoxyacetone is a hygroscopic, white powder with a minty odor. It is abundantly found in nature as derivative of starch and is an intermediate product of fructose metabolism. Acronymed as DHA, it is at large used in the cosmetic industry.
The sunless tanning industry has experienced rapid growth due to public education on the dangers of ultraviolet radiation on skin and improvements in products. Dihydroxyacetone (DHA) is a 3-carbon sugar allowed by the Food and Drug Administration (FDA) as a color additive in sunless tanning products.
Manufacture
DHA is manufactured by bacterial fermentation of glycerine and alternatively from formaldehyde using formose reaction.
| Synonyms | Chromelin Glycerone 1,3-Dihydroxypropan-2-one |
| CAS no. | 96-26-4 |
| EINECS no. | 202-494-5 |
| Molecular formula | C3H6O3 |
| Molecular weight | 90.08 |
| Structure |  |
| Applications in Medicine |
|---|
| The ketone has a history of medical application. It was used in 1950’s as an oral drug to treat children with glycon storage disorder. |
| Applications in Cosmetics |
|---|
| As skin conditioning agent |
| As reducing agent |
| As tanning agent |
| Applications in Intermediates |
|---|
| DHA is a KRM for manufacture of intermediates including but not limited to: |
| a) Hydroxypyruvic acid b) 1-(4-methylbenzyl)-1H-5-hydroxymethyl-imidazole c) 4-Imidazolemethanol HCl d) Glyceric acid e) DL-Glyceraldehyde f) Mannose g) DL-Arabinose |
| Other Applications |
|---|
| Chromelin is also used as color additive |
| DHA is also reported to be used in winemaking |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | White or off-white powder |
| pH | – | 4.0 – 6.0 |
| Moisture | % | Max 0.40 |
| ROI | % | Max 0.40 |
| Heavy metals | ppm | Max 10.0 |
| Iron as Fe | ppm | Max 25.0 |
| Arsenic | ppm | Max 3.0 |
| Assay | % | Min 98.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
25 kg drum.
REACH Status
Under registration.
ExSyn offers DHA on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
1-(Difluoromethyl)-4-nitro-1H-pyrazole is a difluoromethyl aromatic compound with an active nitro group for reduction. It is used as an organic synthesis key starting material and intermediate in APIs.
1-Bromohexane is an organic liquid belonging to the category of alkyl bromides or bromoalkanes. Its reactivity is due to presence of bromine in the allylic position. Apart from being a useful solvent in organic synthesis, it is used in synthesis of various intermediates.
Valeryl chloride is an organic liquid belonging to the category – acid chloride. It is a versatile reagent in organic syntheses leading to its diverse applications such as synthesis of enzyme inhibitors, production of APIs, intermediates, and agrochemicals.
2-Chloroethylamine hydrochloride is a colourless to off-white solid. It consists of an alkylamine attached to a Chlorine atom. It is a member of the Chloroalkylamines. It is a highly corrosive material to both skin and metals thus it must be handled with extreme care.
Thiophosgene is an organic liquid with a heterogeneous composition. The molecule is a reactive electrophile leading to its applications in APIs, intermediates, and agrochemicals, amongst others.
N.N’-Dicyclohexylcarbodiimide, acronymed as DCCD by chemists, is a versatile reagent in organic syntheses. Its reactivity is due to the presence of carbodiimide group in its structure.
Sodium bromide is an inorganic compound with the formula NaBr. It is a high-melting white, crystalline solid that resembles sodium chloride. It is a widely used source of the bromide ion and has many applications.
3,5-Dibromo-4-hydroxybenzoic acid is an alkylated aromatic compound with active bromo groups. They enable its multiple usages such as organic synthesis reagent, biological stain, and enzyme inhibitor. The compound is also a key intermediate in production of APIs.
Bakuchiol is known as Vegan Retinol as it has ability to improve uneven skin tone by reducing the appearance of dark spots and pigmentation. It is best in class of anti-aging and anti-wrinkles effect.