INTRODUCTION
Acryloyl chloride is an organic liquid from the class of acid chlorides. It is a toxic and lachrymatic chemical that has a variety of applications in APIs, intermediates and polymers.
Manufacture
It is manufactured by chlorination of acrylic acid by phosphorus oxychloride.
| Synonym | 2-Propenoyl chloride Acrylic acid chloride |
| CAS # | 814-68-6 |
| EINECS # | 212-399-0 |
| Molecular formula | C3H3ClO |
| Molecular weight | 90.51 |
| Structure | ![]() |
Applications
APIS
| Poziotinib (an anti-cancer drug) |
| Ibrutinib (also an anti-cancer drug) |
Intermediates
| 1-(2,3-Dihydro-1H-indol-1-yl)-2-propene-1-one |
| N-Isopropylacrylamide |
| N-Acryloxysuccinimide |
| 1,4-Diacryloylpiperazine |
| Dodecyl acrylate |
Polymers
| Acrylic polymers |
| Poly(styrene-acryloyl chloride)copolymer |
| Acrylate-based conducting polymers |
Others
| Used as building block to introduce acrylic group in organic compounds |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Colourless to pale yellow liquid |
| Identification by GC | – | Main peak for sample solution should correspond to that of standard solution |
| Specific gravity at 30 deg cel | – | 1.112 – 1.116 |
| Purity by GC | % | Min 98.00% |
| Acrylic acid by GC | % | Max 1.00% |
| 3-Chloropropionyl chloride by GC | % | Max 0.50% |
| Total impurities by GC | % | Max 2.00% |
| BHT as stabilizer | ppm | Max 500 |
STORAGE
Recommended storage temperature : 2° to 8°C
Shipped under temperature-controlled conditions
PACKING
100 kg UN-approved HDPE drum
REACH Status
Not registered
ExSyn offers acryloyl chloride on commercial scales at refrigerated temperature and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Blown Castor Oil (15-17 Poise) is a modified grade of Castor oil. The “15-17 Poise” specification refers to its viscosity range, indicating a medium-viscosity blown oil suitable for industrial applications requiring improved body, tackiness, and elasticity compared to regular castor oil.
Dimethylaminoethanol (DMAE) is a is a tertiary amine that is ethanolamine having two N-methyl substituents. It is clear & colourless to pale yellow liquid with ammoniacal odor. DMAE is stable at room temperature and is completely miscible with water as well as organic solvents such as alcohols and ethers. It decomposes at high temperatures. It is a versatile chemical intermediate primarily used as a curing agent for polyurethane foams and epoxy resins.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.
Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.
Methyl-2-Methoxy-5-Sulfamoyl Benzoate (MSMB) is a sulfur containing organic building block acting as a chemical intermediate. MSMB contains ester and sulfamoyl functional groups, which make it useful as a pharmaceutical and fine-chemical intermediate.
Imidazolidinyl urea is a widely used antimicrobial preservative in the cosmetic and personal care industry. It is a formaldehyde-releasing compound that effectively inhibits the growth of bacteria, yeast, and molds, thereby extending the shelf life of formulations. Due to its broad-spectrum efficacy and cost-effectiveness, it is commonly used in rinse-off and leave-on products within regulated concentration limits.
Phosphorodiamidites are a unique class of phosphorus-based compounds characterized by one P–O bond and two P–N moieties. 2-Cyanoethyl tetraisopropylphosphorodiamidite plays a crucial role in solid-phase oligonucleotide synthesis. Beyond their application as synthetic precursors for oligonucleotides, phosphorodiamidites have also been reported as valuable starting materials for the synthesis of industrially relevant polymers and flame-resistant materials, including adhesives, coatings, and laminates.
Ferric maltol is an oral iron complex composed of ferric iron (Fe³⁺) chelated with maltol, designed to improve iron absorption while reducing common gastrointestinal side effects associated with traditional iron salts. It is primarily used in the management of iron deficiency with better tolerability.
Phosphatidylcholine (PC) is one of the most important phospholipids derived from soya lecithin and represents a key structural component of cell membranes. Phosphatidylcholine 90% refers to a highly purified grade where the PC content is enriched to around 90% through specialized extraction and purification steps.
