INTRODUCTION
o-Nitrophenyl Disulfide is a chemical compound used in organic chemistry and biochemistry. It is a disulfide derivative where two o-nitrophenyl groups are connected by a disulfide bond (-S-S-). It is used in various organic synthesis reactions, as a reagent in the preparation of thiol-reactive compounds, in pharmaceutical research and laboratory applications.
Manufacture
Synthesis process typically involves dissolution of o-nitrophenyl mercaptan in an organic solvent such as dichloromethane and subsequently oxidising it using hydrogen peroxide (H2O2) or iodine. Final compound is further purified through recrystallisation.
| Synonyms | Bis(2-nitrophenyl) disulfide; 2-Nitrophenyl Disulfide; 1,2-bis(2-nitrophenyl) disulfane |
| CAS no. | 1155-00-6 |
| EINECS no. | 214-581-5 |
| Molecular formula | C12H8N2O4S2 |
| Molecular weight | 308.33 |
| Structure |  |
Applications
Its applications span across various fields of organic synthesis, biochemistry, and analytical chemistry.
| In Biochemical research to study protein modification and cross-linking of enzyme-substrate interactions or creating enzyme complexes. |
| In disulfide bond formation in proteins. |
| As a Thiol-reacting reagent help researchers analyze protein structure and interactions. |
| In organic synthesis for sulfuration and electrophilic substitution reactions. |
| Used in creation of polymer cross-links. |
| Used in the modification of synthetic rubbers or plastics. |
| In Pharmaceutical and drug discovery research it is used as a precursor in the synthesis of other disulfide-containing molecules. |
| For synthesizing functionalized aromatic compounds. |
| In analytical chemistry used as a probe to study thiol-containing molecules and in UV-Vis spectroscopic studies. |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Yellow solid |
| Purity | % | Min. 98.00 |
STORAGE
Tightly closed and away from sources of ignition and heat.
PACKING
25 Kg HDPE Drums
REACH Status
Not registered
ExSyn offers o-Nitrophenyl Disulfide on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.
Blown Castor Oil (15-17 Poise) is a modified grade of Castor oil. The “15-17 Poise” specification refers to its viscosity range, indicating a medium-viscosity blown oil suitable for industrial applications requiring improved body, tackiness, and elasticity compared to regular castor oil.
Dimethylaminoethanol (DMAE) is a is a tertiary amine that is ethanolamine having two N-methyl substituents. It is clear & colourless to pale yellow liquid with ammoniacal odor. DMAE is stable at room temperature and is completely miscible with water as well as organic solvents such as alcohols and ethers. It decomposes at high temperatures. It is a versatile chemical intermediate primarily used as a curing agent for polyurethane foams and epoxy resins.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.
Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.
Methyl-2-Methoxy-5-Sulfamoyl Benzoate (MSMB) is a sulfur containing organic building block acting as a chemical intermediate. MSMB contains ester and sulfamoyl functional groups, which make it useful as a pharmaceutical and fine-chemical intermediate.
Imidazolidinyl urea is a widely used antimicrobial preservative in the cosmetic and personal care industry. It is a formaldehyde-releasing compound that effectively inhibits the growth of bacteria, yeast, and molds, thereby extending the shelf life of formulations. Due to its broad-spectrum efficacy and cost-effectiveness, it is commonly used in rinse-off and leave-on products within regulated concentration limits.
Phosphorodiamidites are a unique class of phosphorus-based compounds characterized by one P–O bond and two P–N moieties. 2-Cyanoethyl tetraisopropylphosphorodiamidite plays a crucial role in solid-phase oligonucleotide synthesis. Beyond their application as synthetic precursors for oligonucleotides, phosphorodiamidites have also been reported as valuable starting materials for the synthesis of industrially relevant polymers and flame-resistant materials, including adhesives, coatings, and laminates.
Ferric maltol is an oral iron complex composed of ferric iron (Fe³⁺) chelated with maltol, designed to improve iron absorption while reducing common gastrointestinal side effects associated with traditional iron salts. It is primarily used in the management of iron deficiency with better tolerability.