INTRODUCTION

N-acetylsulfanilyl chloride is a white coloured powder, soluble in organic solvents and slightly soluble in water. It is a versatile chemical compound that has numerous applications in industries, such as Agro and Pharmaceuticals.

MANUFACTURE

It is synthesized by the reaction of 4-chlorobenzenesulfonyl chloride with acetic acid in the presence of a catalyst like aluminum chloride.

Synonyms4-Acetamidobenzenesulfonyl chloride
Acetanilide 4-sulfonyl chloride
4-Acetylaminobenzenesulfonyl chloride
CAS no.121-60-8
EINECS no.204-485-1
Molecular formulaC8H8ClNO3S
Molecular weight233.66
Structure

APPLICATIONS

Is a key component in the synthesis of pharmaceuticals, including sulfa drugs and antibiotics, contributing to the healthcare sector’s growth.
It plays a crucial role in the production of dyes and pigments, used extensively in textiles, paints, and plastics.
It acts as a valuable chemical reagent for various chemical reactions, making it indispensable in laboratory research and industrial processes.
Used in the manufacturing of Sulfonylurea herbicides, used to control weeds in crops.

SPECIFICATIONS

TestUnitSpecification
DescriptionDull white colored powder with characteristic odor
Identification
1. Test A (by IR)To match with working standard
2. Test B (chemical test)To a cooled solution of 20 mg of sample in 2 ml. Acetone, add 1ml of 1% NaNO2 solution produces pale yellow color. On addition of 2 ml of 1% α – Naphthol solution in 20% NaOH solution it produces orange-red colored upper layer
Moisture content% w/wNMT 0.30
Melting range°C143.0 – 147.0
Free aciditymlNMT 0.5 ml of 0.1 M NaOH per gm
Assay% w/wNLT 99.0

PACKING

25 kg UN approved HDPE drum.

STORAGE

Store in closed container in a dry area.

REACH status

Not registered.

No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.

More Products
In focus: Nikethamide BP (N,N-Diethylnicotamide)
Products in focus · 25/08/2026

Nikethamide is a synthetic organic compound derived from nicotinic acid (vitamin B₃). It consists of a pyridine ring linked to a diethyl amide functional group and belongs to the class of pyridine amide derivatives.

READ MORE
In focus: (2-Methoxy-1-methyl-2-oxoethyl)triphenylphosphoniumbromide
Products in focus · 18/08/2026

(2-Methoxy-1-methyl-2-oxoethyl)triphenylphosphonium bromide is a stabilized phosphonium salt widely used as an intermediate in organic synthesis. Due to presence of an ester group, the compound generates a stabilized ylide that is particularly useful for synthesizing α, β-unsaturated esters, valuable intermediates in pharmaceuticals, agrochemicals, fragrances, and fine chemicals.

READ MORE
In focus: p-tert-butylphenol (PTBP)
Products in focus · 11/08/2026

p-tert-Butylphenol (PTBP), is an aromatic organic compound consists of a phenol ring substituted with a tert-butyl group at the para (4-) position, giving it improved thermal stability and hydrophobic properties compared to phenol. PTBP features significant hydrogen bonding capabilities, which enhance its solubility in organic solvents. PTBP is used primarily as an intermediate in the manufacturing of polycarbonate plastics, phenolic resins, and epoxy resins.

READ MORE
In focus: Yttrium oxide
Products in focus · 04/08/2026

Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.

READ MORE
In focus:Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate
Products in focus · 28/07/2026

Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate is a fluorinated aliphatic hydroxy ester. The presence of the trifluoromethyl group imparts enhanced metabolic stability, lipophilicity, and unique physicochemical properties compared with non-fluorinated analogues. This compound is primarily used as a synthetic intermediate in pharmaceutical and agrochemical research.

READ MORE
In focus: 2-Chloro-1,1,1- trimethoxyethane
Products in focus · 21/07/2026

2-Chloro-1,1,1-trimethoxyethane is an organochlorine orthoester compound commonly used as a versatile synthetic intermediate in organic and pharmaceutical chemistry. It is a colorless to pale yellow liquid with good reactivity toward nucleophilic substitution and cyclization reactions, making it valuable in the preparation of heterocyclic and bioactive molecules.

READ MORE
In focus: Glycolaldehyde Dimer
Products in focus · 14/07/2026

Glycolaldehyde dimer is the cyclic dimeric form of glycolaldehyde, the simplest hydroxyaldehyde. Glycolaldehyde is often supplied as stable dimeric solid, commonly identified as 2,5-dihydroxy-1,4-dioxane.

READ MORE
In focus: N,N Diisopropylethylamine
Products in focus · 07/07/2026

N,N-Diisopropylethylamine (DIPEA), also known as Hünig’s Base, is a sterically hindered tertiary amine. It is a colorless liquid with a strong amine odor and is widely used as a low nucleophilic organic base in pharmaceutical, agrochemical, and fine chemical synthesis. Due to its bulky structure, DIPEA effectively scavenges acids without participating in unwanted side reactions.

READ MORE
In focus: Tris(2,4-ditert-butylphenyl) Phosphite
Products in focus · 30/06/2026

Tris(2,4-di-tert-butylphenyl) phosphite (TDPP) often recognized commercially as Irgafos 168 is a high-performance organophosphorus compound primarily utilized as secondary antioxidant and processing stabilizer. Its characteristic to undergo metallation reaction and provide a cost-effective synthetic processes allows it to be useful in biaryl coupling reactions.

READ MORE