INTRODUCTION
Glycidol is a viscous organic compound that belongs to the class of beta-oxyalcohols. Its reactivity is attributed to the epoxy moiety at beta position. The alcohol finds applications majorly in APIs, glycidyl esters and ethers, and in alkanolamines.
Manufacture
It is manufactured from 2-Chloro-1,3-propanediol in a catalyzed ring closure process. The unreacted reactant is removed by distillation
| Synonym | Oxiran-2-ylmethanol 1,2-Epoxy-3-hydroxypropane |
| CAS # | 556-52-5 |
| EINECS # | 209-128-3 |
| Molecular formula | C3H6O2 |
| Molecular weight | 74.08 |
| Structure |  |
Applications
APIS
-S-(-)-Atenolol (Beta-blocker)
-Guaifenesin (Expectorant)
-Indivir sulphate (Anti-retroviral)
-Leinamycin (Antibiotic)
-Levodropropizine (Antitussive)
-Propanolol (Beta-blocker)
Intermediates
-Alkanolamines
-Polyglycerols
-Glycidyl methacrylate
-Glycidyl fatty acid esters
Others
-Production of non-ionic surfactants based on fatty alcohols
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | Colourless transparent liquid |
| Identification by IR | – | Should conform to the reference spectrum |
| Identification by proton NMR | – | Should conform to the structure |
| Specific Gravity | g/cm3 | 1.10 -1.20 |
| Moisture | Wt % | Max 0.5 |
| Assay by GC | % | Min 97.0 |
| Assay by titrimetry | % | Min 97.0 |
STORAGE
Recommended storage temperature – 2° to 8°C
Shipped under temperature-controlled conditions
PACKING
50 kg /200 kg UN-approved HDPE drum
REACH Status
Not registered
ExSyn offers glycidol on commercial scales at refrigerated temperature and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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