INTRODUCTION
Pyrophosphoryl chloride is colourless to pale yellow liquid, reasonably easy to handle. It reacts violently with water & miscible with most organic solvents.
It is used in pharmaceutical and other organic synthesis, as laser materials and electronic components.
Manufacture
Pyrophosphoryl chloride is prepared by reacting dichlorophosphoric acid, or a mixture containing the acid with phosphorus pentachloride in the absence of water.
| Synonyms | Pyrophosphoric tetrachloride Pyrophosphoryl chloride Diphosphoric tetrachloride |
| CAS no. | 13498-14-1 |
| EINECS no. | 236-824-4 |
| Molecular formula | P2O3Cl4 |
| Molecular weight | 251.76 |
| Structure |  |
Applications
| Pyrophosphoryl chloride serves as a reductive chlorination reagent used in the synthesis of quetiapine. |
| It acts as a phosphorylating agent involved in nucleoside synthesis. |
| It plays an important role in Vilsmeier formylation and glyoxylation reactions. |
| Diphosphoryl chloride is used in the synthesis of potent and orally bioavailable tricyclic CGRP receptor antagonists. |
| Also used in the synthesis of transition state analogue inhbitors of inosine monophosphate. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Characteristics | – | Colorless, smoking, corrosive liquid |
| Specific gravity | – | 1.80 – 1.82 |
| Assay by Chloride | % | Min 99.0 |
| Assay by Acidimetric | % | Min 99.0 |
STORAGE
Moisture Sensitive. Air Sensitive. Store under Nitrogen. Ambient temperatures.
PACKING
40 kg UN approved carboys.
REACH Status
Not registered yet.
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Zinc Dialkyl Dithio Phosphate (ZDDP) belongs to a family of coordination compounds classified as members of transition metal dithiophosphate.
ZDDP is widely used based on a combination of different selected alcohols thus providing antiwear performance and enhanced thermal and hydrolytic stability. In combination with other additives, it is especially used for the formulation of hydraulic fluids, industrial gear oils, metalworking fluids, greases and automotive engine oils.
Dibutyl sulfide is an organosulfur. It is a clear, colorless to pale yellow liquid characterized by a strong sulfur-like odor and is primarily used as an intermediate in chemical synthesis, specialty organic manufacturing, and research applications. The compound exhibits good solvency properties and moderate thermal stability, making it useful in industrial and laboratory processes involving sulfur-containing organic compounds.
Oleylamine is a long-chain (C18) primary fatty amine derived from natural fatty acids, typically sourced from vegetable oils. It is produced from oleic acid through conversion of the carboxylic acid group (–COOH) into an amine group (–NH₂). With its optimal balance of hydrophobic chain length and reactive amine functionality it serves as a versatile and dependable building block for high-performance formulations.
Sodium Hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring glycosaminoglycan known for its exceptional ability to retain moisture, along with its viscoelastic and biocompatible properties, making it highly valuable across pharmaceutical, cosmetic, and biomedical applications.
Pyrazinamide is a first-line antitubercular drug used in combination therapy for the treatment of tuberculosis (TB). It is a synthetic pyrazine derivative and acts as a prodrug, which is converted into its active form (pyrazinoic acid) inside Mycobacterium tuberculosis.
6-Bromopyridine-2,3-diamine is a heterocyclic organic compound belonging to the class of substituted pyridines. It is used mainly as an intermediate in pharmaceuticals and agrochemicals.
Magnesium trisilicate is an inorganic compound commonly used in pharmaceutical and gastrointestinal (GI) preparations due to its dual action. It is usually produced as a white, odorless, fine powder. It helps bind toxins or irritants in the gastrointestinal tract and occasionally used in formulations for its stabilizing properties.
Choline salicylate is a salicylate salt formed from choline and salicylic acid. It is a non-steroidal anti-inflammatory agent (NSAID-type compound) mainly used for its analgesic, anti-inflammatory, and mild antiseptic properties. Unlike acetylated salicylates, it is less irritating to the gastric mucosa and is commonly used in topical oral preparations such as gels and mouth paints.
TensyraTM N-10 (Octoxinol 10; tert-octyl phenyl ethoxylate) is a non-ionic surfactant known for its excellent solubilizing and membrane-permeabilizing properties. It features a hydrophilic polyethylene oxide chain paired with a lipophilic aromatic hydrocarbon group.It readily breaks down biological membranes to lyse cells, solubilize proteins, and permeabilize cell membranes for assays.