INTRODUCTION
The aromatic is a liquid with a pleasant odor. The active methoxy group attached to a benzene ring renders a high amount of reactivity to the molecule. Worldwide, anisole is commercially produced by methylation of phenol.
| Synonyms | Methoxybenzene Phenyl Methyl Ether Methyl Phenyl Ether |
| CAS no. | 100-66-3 |
| EINECS no. | 202-876-1 |
| Molecular formula | C7H8O |
| Molecular weight | 108.14 |
| Structure |  |
APPLICATIONS
Anisole is used in various industry verticals including but not limited to manufacture of API, colorants, cosmetics, flavor & fragrance chemicals, polymerization inhibitors, antioxidants, and agrochemicals. It is also consumed as solvent in various chemicals processes.
| Pharmaceuticals | The sweet aromatic is a key starting compound in the manufacture of Tamoxifen, Guaifenesin, Carvedilol, Ranolazine and Methocarbamol. In the process, anisole is first converted into Guaiacol, which is an antioxidant. Guaiacol is then used to synthesize some of the above APIs. |
| Agrochemicals | The methoxylated benzene acts as an insect pheromone and it also finds usage in manufacture of Ancymidole (a plant growth regulator) and Methoxychlor (an insecticide). |
| Flavors, Fragrances, and Cosmetics | The aromatic compound is extensively employed, thanks to its odor, for production of F&F chemicals such as Anethole, p-anisaldehyde, Guaiacol, 4-methoxyacetophenone, etc. From the last compound, cosmetic ingredient Avobenzone is manufactured. |
| Inhibitor | A feeble but important use of anisole is in production of methyl ether of hydroquinone (MEHQ), which is one of the universal polymerization inhibitors. |
| Colorant | Anisole is a KRM in the manufacture of the dye Disperse Blue 73 from Acid Blue 45. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Clear colorless liquid |
| Purity by GC | % | NLT 99.5 |
| Phenol Content by GC | ppm | NMT 50 |
| KF Moisture | % | NMT 0.1 |
| Iron | ppm | NMT 5 |
REACH status
Anisole offered by ExSyn is registered as Transported Isolated Intermediate (TII) under the EU REACH regulation.
STORAGE
Product is stored at ambient temperature.
PACKING
The product is offered in drum packing as well as ISO-tanks.
ExSyn offers this compound on commercial scale and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice ! If you need any additional information or SDS, please get in touch with us.
p-tert-Butylphenol (PTBP), is an aromatic organic compound consists of a phenol ring substituted with a tert-butyl group at the para (4-) position, giving it improved thermal stability and hydrophobic properties compared to phenol. PTBP features significant hydrogen bonding capabilities, which enhance its solubility in organic solvents. PTBP is used primarily as an intermediate in the manufacturing of polycarbonate plastics, phenolic resins, and epoxy resins.
Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.
Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate is a fluorinated aliphatic hydroxy ester. The presence of the trifluoromethyl group imparts enhanced metabolic stability, lipophilicity, and unique physicochemical properties compared with non-fluorinated analogues. This compound is primarily used as a synthetic intermediate in pharmaceutical and agrochemical research.
2-Chloro-1,1,1-trimethoxyethane is an organochlorine orthoester compound commonly used as a versatile synthetic intermediate in organic and pharmaceutical chemistry. It is a colorless to pale yellow liquid with good reactivity toward nucleophilic substitution and cyclization reactions, making it valuable in the preparation of heterocyclic and bioactive molecules.
Glycolaldehyde dimer is the cyclic dimeric form of glycolaldehyde, the simplest hydroxyaldehyde. Glycolaldehyde is often supplied as stable dimeric solid, commonly identified as 2,5-dihydroxy-1,4-dioxane.
N,N-Diisopropylethylamine (DIPEA), also known as Hünig’s Base, is a sterically hindered tertiary amine. It is a colorless liquid with a strong amine odor and is widely used as a low nucleophilic organic base in pharmaceutical, agrochemical, and fine chemical synthesis. Due to its bulky structure, DIPEA effectively scavenges acids without participating in unwanted side reactions.
Tris(2,4-di-tert-butylphenyl) phosphite (TDPP) often recognized commercially as Irgafos 168 is a high-performance organophosphorus compound primarily utilized as secondary antioxidant and processing stabilizer. Its characteristic to undergo metallation reaction and provide a cost-effective synthetic processes allows it to be useful in biaryl coupling reactions.
Undecylenic acid is an unsaturated fatty acid naturally derived from castor oil. It is a colorless to pale yellow liquid with antifungal and antimicrobial properties. Chemically known as 10-undecenoic acid, it contains an 11-carbon chain with one double bond and is widely used in pharmaceuticals
5-Nitro Isophthalic Acid (5-NIPA) is an aromatic organic compound derived from isophthalic acid. The presence of two carboxylic acid groups along with a nitro substituent at the 5-position makes it a valuable intermediate in the manufacture of fine chemicals, pharmaceuticals, dyes, pigments, and advanced materials.