INTRODUCTION
Niacinamide is a naturally occurring nutrient belonging to the pyridine carboxylic acid family. It is an important form of vitamin B3, an essential nutrient that supports many cellular processes and plays an important role in energy metabolism. Animal and refined grain-based products are fortified with Niacinamide.
It is a water-soluble vitamin that promotes release of energy from foods and enhances proper nervous system functioning. Along with systemic benefits, it also offers a wide range of topical benefits. Also, it is the preferred form of Vitamin B3 for treating Pellagra.
| Synonym | Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP, 3- Pyridinecarboxamide, Beta Pyridinecarboxamide |
| CAS no. | 98-92-0 |
| EINECS no. | 202-713-4 |
| Chemical Formula | C6H6N2O |
SPECIFICATIONS | Niacinamide Ph.Eur
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | White or almost white crystalline powder or colorless crystals |
| pH | – | 6.0 – 7.5 |
| Assay on dried substance (Chemical – Titrimetic) | – | 99.0 – 101.0 |
| Loss on Drying | % w/w | Max 0.5 |
| Unspecified impurity | % | Max 0.10 |
| Total Impurities | % | Max 0.2 |
| Sulfated Ash | %w/w | Max 0.1 |
APPICATIONS
Common applications for niacinamide are in food, feed and beverages, health and personal care and the pharmaceutical industry. Niacinamide has several other health benefits and uses as follows:
HELPFUL FOR SKIN CARE & IN PREVENTING SKIN CANCER
Niacinamide plays an important role in keeping the skin healthy. For this reason, it’s a popular additive in the cosmetic and skincare industry. When applied topically or taken orally as a supplement, niacinamide has been shown to have anti-inflammatory effects on the skin. It has been used to treat skin conditions like acne and rosacea, a facial skin disorder characterized by redness.
t is also a promising supplement which may help in preventing Melanoma which is a serious type of skin cancer that develops in the cells that produce melanin, the pigment that gives your skin its color. Owing to its role in keeping your cells healthy, oral supplements of niacinamide have been shown to enhance DNA repair in UV damaged skin in humans.
THERAPEUTIC BENEFITS / USES
Chronic kidney disease is the progressive loss of kidney function which can cause a harmful buildup of chemicals.
Research suggests that niacinamide may help decrease phosphate levels in people with kidney dysfunction by blocking its absorption. It’s been suggested that niacinamide protects and preserves the beta cells, thereby preventing or delaying the onset of type 1 diabetes in at-risk individuals.
| INDUSTRY | APPLICATIONS |
|---|---|
| Food & Beverage | Nutrient supplement in foods such as dairy, breakfast cereals & infant formulas, as an additive in beverages, energy/health drinks |
| Health & Personal Care | Used in formulations of foundations, moisturizers, skin care products, lipsticks and eye shadows |
| Pharmaceuticals | Predominantly used as a dietary supplement & vitamin supplement in health drinks and also used in antipellagra factor drug |
| Animal Feed | Nutritional supplement in animal feed as well as pet food |
REGISTRATIONS / CERTIFICATIONS
| WHO-GMP |
| FAMI-QS |
| HACCP |
| Kosher |
| Halal |
PACKAGING OPTIONS
| Bulk Bags |
| HDPE/Fibre Drums |
STORAGE
Store in a sheltered place away from sources of heat and moisture.
Niacinamide is offered by ExSyn and is available for prompt delivery. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
5-Methyl-3-vinyl-2-oxazolidinone (V-MOX) is a highly reactive monomer valued for its low viscosity, mild odor, and excellent reactivity. It is widely used as a reactive diluent in UV-curable inks and coatings, where it enhances adhesion, produces brighter colors, and improves safety compared to conventional diluents. In addition, V-MOX serves as a key building block in the synthesis of kinetic hydrate inhibitor (KHI) polymers, which are applied in oil and gas production to prevent hydrate blockages in pipelines.
Zinc ricinoleate is the zinc salt of ricinoleic acid, a hydroxylated fatty acid derived mainly from castor oil (Ricinus communis). It appears as a white to slightly yellowish powder, waxy solid, or paste, depending on formulation. Its most valuable property is its ability to trap and absorb odor molecules such as amines, sulfides, and short-chain fatty acids, making it an essential ingredient in deodorant and odor-control products.
2-(tert-Butyl amino)ethyl methacrylate (TBAEMA) is a functional methacrylate monomer that contains a secondary amine group and a hydrophobic tert-butyl moiety, giving it excellent versatility in pH-responsive and adhesion-enhancing polymer systems.
It is valued in printing ink formulations for its ability to enhance adhesion, flexibility, and surface interaction.
Commonly known as potassium bis(fluorosulfonyl)imide (KFSI), the compound has a three-carbon backbone bearing six fluorine atoms and two sulfonimide (-SO₂F) groups. The molecule’s architecture lends it both high chemical stability and useful reactivity. Because of its excellent ionic conductivity and thermal / electrochemical stability, it finds use in advanced electrolyte formulations—for example in lithium-ion and next-generation batteries, in ionic liquids, and in other electrochemical systems.
Colchicine is a naturally occurring alkaloid obtained primarily from the autumn crocus (Colchicum autumnale) and related species. It has been used in medicine for centuries, especially for the treatment of gout and Familial Mediterranean Fever. In modern medicine, Colchicine is valued also in conditions like pericarditis, Behçet’s disease, and certain dermatological and cardiac disorders.
1-Butylimidazole is a versatile organic heterocyclic compound belonging to the imidazole family, where a butyl group (–CH₂–CH₂–CH₂–CH₃) is attached to the nitrogen atom at the 1-position of the imidazole ring. Its applications span organic synthesis, materials science, and bioactive compound development due to its tunable physicochemical properties and structural versatility.
Atropine sulfate monohydrate is a chemical compound, specifically a salt of atropine and sulfuric acid, with one water molecule (monohydrate) attached. It is commonly used as a medication and in research due to its anticholinergic properties, meaning it blocks the effects of acetylcholine at muscarinic receptors.
4-Aminobenzoic acid, commonly abbreviated as PABA, is an aromatic amine and carboxylic acid compound. It consists of a benzene ring substituted with an amino group (–NH₂) in the para position to a carboxylic acid group (–COOH).
2-Amino-5-Nitrophenol (5-NAP) is an organic compound with the molecular formula C₆H₆N₂O₃. It is a substituted phenol with both an amino group (-NH₂) and a nitro group (-NO₂) attached to a benzene ring, along with a hydroxyl group (-OH).