INTRODUCTION
Ferrozine, chemically 3-(2-Pyridyl)-5,6-bis(4-phenylsulfonic acid)-1,2,4-triazine disodium salt, is a water-soluble solid. It is complexometric reagent for detection and estimation of iron.
Manufacture
It is synthesized by condensation of 2,6-dimethyl pyridine with 3,5-dinitrobenzenesulfonic acid, followed by reduction with Fe powder, and then sulfonation with fuming sulfuric acid. Purification occurs via crystallization from water.
| Synonym | 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-4´,4´´-disulfonic acid sodium salt |
| CAS no. | 28048-33-1 |
| EINECS no. | 248-797-6 |
| Molecular formula | C20H12-13N4Na1-2O6S2·xH2O |
| Molecular weight | 468.47 (anion) |
| Structure |  |
| Applications |
|---|
| Determine the iron content in food, water, chemicals, and biological samples |
| Study the metabolism of iron in cells and tissues |
| Monitor the environmental pollution caused by heavy metals |
| Preparation of iron complexes for catalysis |
| Synthesis of iron nanoparticles for biomedicine |
| Develop new sensors, biomaterials, and drug delivery systems |
| Improve efficacy and safety of existing medicinal treatments |
| Numerous other applications in scientific experiments, especially in the fields of analytical chemistry, biochemistry, and environmental science |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Greenish yellow powder |
| Solubility (C5%; w/v. in acetate buffer, pH 5.5) | – | Yellow, clear |
| Identification by UV (c = 1%, w/v, d = 1 cm) | – | Should correspond to standard Max 282-284 nm Specific Extinction at absorption Max 385-465 |
| Identification by IR | – | Should correspond to standard |
| Sodium by flame photometry, based on hydrous substance | % | 4.0 – 9.0 |
| KF Water | % | ≤10.0 |
| Assay Ferrozine anion (Photometric), based on hydrous substance | % | 90.0 – 110.0 |
STORAGE
Stored at ambient temperature.
PACKING
25 kg drum.
REACH Status
Not registered yet.
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