INTRODUCTION
3- Bromothianisole is a brominated aromatic compound with an active methyl thio group for oxidation. It has many applications in pharmaceutical and biotech industries as an intermediate for the synthesis of various organic compounds. It also holds miscellaneous applications in medicinal chemistry, agrochemicals, and material science.
Manufacture
It is manufactured by diazotisation of 3-bromoanline.
| Synonym | 1-Bromo-3-(methylthio)benzene, 3-Bromophenyl Methyl Sulfide |
| CAS no. | 33733-73-2 |
| Molecular formula | C7H7BrS |
| Molecular weight | 203.1 |
| Structure |  |
Applications
| APIs– 3-Bromothioanisole is used in synthesis of the following APIs: |
|---|
| Pridopidine, Sigma-1 receptor (S1R) agonist. |
| Pridopidine Hydrochloride used to investigational drug research for Huntington’s Disease (HD) and Amyotrophic Lateral -Sclerosis (ALS) diseases. |
| Intermediates |
|---|
| 1-Bromo-3-(methylsulfonyl)benzene |
| 3-methylthiotriphenylamine |
| 4-ethoxy-3′-methylthiostilbene |
| 3-bromophenyl phenyl sulfide |
| 9-substituted, 3,6-dithiomethylfluorenes |
| 4-methoxy-3′-(methylthio)-1,1′-biphenyl |
SPECIFICATIONS
| Test | Unit | Specifications |
| Appearance | – | Clear colorless to yellow liquid |
| Purity by GC | % | Min 97.0 |
STORAGE
Stored at ambient temperature
PACKING
25 Kg HDPE Carboys
REACH Status
Not registered
ExSyn offers 3-Bromothioanisole on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.
Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.
Methyl-2-Methoxy-5-Sulfamoyl Benzoate (MSMB) is a sulfur containing organic building block acting as a chemical intermediate. MSMB contains ester and sulfamoyl functional groups, which make it useful as a pharmaceutical and fine-chemical intermediate.
Imidazolidinyl urea is a widely used antimicrobial preservative in the cosmetic and personal care industry. It is a formaldehyde-releasing compound that effectively inhibits the growth of bacteria, yeast, and molds, thereby extending the shelf life of formulations. Due to its broad-spectrum efficacy and cost-effectiveness, it is commonly used in rinse-off and leave-on products within regulated concentration limits.
Phosphorodiamidites are a unique class of phosphorus-based compounds characterized by one P–O bond and two P–N moieties. 2-Cyanoethyl tetraisopropylphosphorodiamidite plays a crucial role in solid-phase oligonucleotide synthesis. Beyond their application as synthetic precursors for oligonucleotides, phosphorodiamidites have also been reported as valuable starting materials for the synthesis of industrially relevant polymers and flame-resistant materials, including adhesives, coatings, and laminates.
Ferric maltol is an oral iron complex composed of ferric iron (Fe³⁺) chelated with maltol, designed to improve iron absorption while reducing common gastrointestinal side effects associated with traditional iron salts. It is primarily used in the management of iron deficiency with better tolerability.
Phosphatidylcholine (PC) is one of the most important phospholipids derived from soya lecithin and represents a key structural component of cell membranes. Phosphatidylcholine 90% refers to a highly purified grade where the PC content is enriched to around 90% through specialized extraction and purification steps.
Indorez® Kota Resin is a modified non self-cured phenolic resin, it can increase rubber adhesion to steel, polyester, rayon, nylon, aramid and other fabric cord. It’s an adhesive agent, acts as methylene acceptor, can 100% replace resorcinol and resorcinol resins in resorcinol- formaldehyde-silica, enhance adhesion between rubber and reinforcing materials.
Glyceryl Stearate Citrate (GSC) is a plant-derived, biodegradable emulsifier commonly used in cosmetics and personal-care products. It functions primarily as an anionic oil-in-water (O/W) emulsifier, helping blend oils and water into smooth, stable creams and lotions. Its natural origin and gentle profile make it popular in eco-certified, organic, and sensitive-skin formulations.