INTRODUCTION
2-Cyclohexene-1-one is an organic intermediate used in synthesis of pharmaceuticals, agrochemicals, and fragrances. It is a ketone, or more precisely, an enone. It undergoes nucleophilic conjugate addition with organocopper reagents, Michael reactions and Robinson annulations.
Manufacture
The product is commercially manufactured by Birch reduction of phenol or anisole, alternatively by catalytic oxidation of cyclohexene.
| Synonyms | Cyclohexenone Cyclohex-2-enone |
| CAS no. | 930-68-7 |
| EINECS no. | 212-223-5 |
| Molecular formula | C6H8O |
| Molecular weight | 96.13 |
| Structure |  |
Applications in Pharma
| Cyclohexenone is a key raw material in the production of: |
|---|
| Carprofen, a nonsteroidal anti-inflammatory drug |
Applications in Agrochemicals
| It is also used to synthesize the herbicides: |
|---|
| Clethodim |
| Tralkoxydim |
Applications in Intermediates
| Following intermediates can be synthesized from cyclohexenone: |
|---|
| 3-Methylcyclohexanone |
| 2-(Hydroxymethyl)cyclohex-2-en-1-one |
Other Applications
| As fragrance ingredient with roasted savory green odor |
| In biological studies for H-tunneling in multiple hydride transfers of catalytic cycle of the enzyme – morphinone reductase |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Clear, colorless or slightly yellowish liquid |
| Identification by GC | – | Peak in the sample chromatogram to match with that in standard chromatogram |
| Water by KF | w/v | Max 0.5 |
| Density at 20°C | – | 0.987 – 0.997 |
| Purity by GC | % | Min 98.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
25 kg UN-approved carboy.
REACH Status
Not registered yet.
ExSyn offers 2-cyclohexene-1-one on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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