INTRODUCTION
Octenidine dihydrochloride is a cationic surfactant, with a gemini-surfactant structure. Since 1987, it has been used primarily in Europe as an antiseptic prior to medical procedures, including on neonates. It is safe to handle and chemically stable.
Manufacture
This quaternary compound salt is derived from octenidine and hydrochloric acid.
| Synonym | N-octyl-1-[10-(4-octyliminopyridin-1-yl)decyl]pyridin-4-imine;dihydrochloride |
| CAS no. | 70775-75-6 |
| EINECS no. | 274-861-8 |
| Molecular formula | C36H64Cl2N4 |
| Molecular weight | 623.83 |
| Structure |  |
APPLICATIONS
| Octenidine dihydrochloride finds extensive application in medical, industrial, and even food and cosmetic realms |
|---|
| Widely recognized for its exceptional antiseptic, antibacterial, and antifungal properties, It is used for the treatment of wound infections and for disinfecting the skin and mucous membrane. |
| Also, it exhibits anti-inflammatory and analgesic properties, providing relief from inflammation and pain. |
| Octenidine dihydrochloride has been subject to extensive in vitro studies. Its efficacy in treating bacterial and fungal infections has been explored, showcasing its effectiveness against both gram-positive and gram-negative bacteria. |
| Researchers have evaluated its potential as a combatant against viruses, revealing its favorable outcomes in combating select viral strains. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description | – | A white to off white powder |
| Solubility | – | Freely soluble in Methanol and Dichloromethane, slightly soluble in N,N‐dimethyl formamide |
| Identification | ||
| a. By IR spectrum | – | a. The IR spectrum of sample should be concordant with that of working standard of Octenidine Dihydrochloride |
| b. Chloride | – | b. It gives reaction for chloride |
| Assay by HPLC | % | Between 98.0 to 101.0 on anhydrous basis |
| Related substances by HPLC | ||
| a. 4-Octyl amino pyridine | % | NMT 0.15 |
| b. Single unknown impurity | % | NMT 0.10 |
| c. Total impurities | % | NMT 0.5 |
| Heavy metals | ppm | NMT 10.0 |
| Sulphated ash | % | NMT 0.5 |
| Water content | % | NMT 2.0 |
| Residual solvents | ||
| Methanol | ppm | NMT 3000 |
| N,N-Dimethyl formamide | ppm | NMT 880 |
| Acetone | ppm | NMT 5000 |
PACKING
25 kg Fiber drum.
STORAGE
Keep containers tightly closed in a dry, cool and well-ventilated place. Store at room temperature.
CERTIFICATION
WHO-GMP and DMF
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.
Ciclopirox Olamine (CPO) is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.
N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.
Blown Castor Oil (15-17 Poise) is a modified grade of Castor oil. The “15-17 Poise” specification refers to its viscosity range, indicating a medium-viscosity blown oil suitable for industrial applications requiring improved body, tackiness, and elasticity compared to regular castor oil.
Dimethylaminoethanol (DMAE) is a is a tertiary amine that is ethanolamine having two N-methyl substituents. It is clear & colourless to pale yellow liquid with ammoniacal odor. DMAE is stable at room temperature and is completely miscible with water as well as organic solvents such as alcohols and ethers. It decomposes at high temperatures. It is a versatile chemical intermediate primarily used as a curing agent for polyurethane foams and epoxy resins.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.
Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.
Methyl-2-Methoxy-5-Sulfamoyl Benzoate (MSMB) is a sulfur containing organic building block acting as a chemical intermediate. MSMB contains ester and sulfamoyl functional groups, which make it useful as a pharmaceutical and fine-chemical intermediate.
Imidazolidinyl urea is a widely used antimicrobial preservative in the cosmetic and personal care industry. It is a formaldehyde-releasing compound that effectively inhibits the growth of bacteria, yeast, and molds, thereby extending the shelf life of formulations. Due to its broad-spectrum efficacy and cost-effectiveness, it is commonly used in rinse-off and leave-on products within regulated concentration limits.