INTRODUCTION
1,3-Dimethyl-2-imidazolidinone, popular as DMI solvent, is a high boiling aprotic polar molecule. Apart from being a common solvent in derivative GC, it finds applications in diverse industrial verticals.
Manufacture
The solvent is produced on large scale from ethylenediamine in a multi-step synthesis that also consumes urea, methyl trioctyl ammonium chloride, and dimethyl sulphate as key raw materials.
| Synonyms | N,N’-Dimethylethyleneurea Dimethylimidazolidionone |
| CAS no. | 80-73-9 |
| EINECS no. | 201-304-8 |
| Molecular formula | C5H10N2O |
| Molecular weight | 114.15 |
| Structure |  |
Applications
| DMI solvent is used in synthesis of: |
|---|
| Mirabegron, a drug that eases symptoms of overactive bladder |
| Itraconazole, an anti-fungal API |
| Donepezil, an API to improve memory and awareness in Alzheimer patients |
| Pigment Blue 60 |
| 4-Chloro-1-benzothiophene |
| 2-Fluoro-5-bromobenzonitrile |
| 1,2-Bis(trimethylsilyl)benzene |
| 3,5-Difluorochlorobenzene |
| The solvent is also used as replacement of the toxic solvent hexamethylphosphoramide. |
| It is applied as humectant in cosmetics and its applications in dyestuffs, electronic materials, cellulose, and polymers are also cited. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Colorless to pale yellow liquid |
| Color | APHA | Max 50.0 |
| Specific gravity at 25 deg cel | – | 1.050 – 1.060 |
| Refractive index | – | 1.468 – 1.473 |
| Moisture by KF | % | Max 1.0 |
| Purity by GC | % | Min 99.0 |
STORAGE
The product is stored at ambient temperature.
PACKING
200 kg HDPE drum.
REACH Status
Not Registered yet.
ExSyn offers 1,3-dimethylimidazolidin-2-one on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Yttrium oxide (Y2O3), also known as yttria, is an air-stable, odorless white powder. It is a highly stable, chemically inert ceramic with a very high melting point. It is insoluble in water but readily dissolves in most strong acids. Increasing the specific surface area and porosity of Y2O3 can further improve its relevant physical and chemical properties.
Ethyl 7,7,7-trifluoro-3-hydroxy-3-methylheptanoate is a fluorinated aliphatic hydroxy ester. The presence of the trifluoromethyl group imparts enhanced metabolic stability, lipophilicity, and unique physicochemical properties compared with non-fluorinated analogues. This compound is primarily used as a synthetic intermediate in pharmaceutical and agrochemical research.
2-Chloro-1,1,1-trimethoxyethane is an organochlorine orthoester compound commonly used as a versatile synthetic intermediate in organic and pharmaceutical chemistry. It is a colorless to pale yellow liquid with good reactivity toward nucleophilic substitution and cyclization reactions, making it valuable in the preparation of heterocyclic and bioactive molecules.
Glycolaldehyde dimer is the cyclic dimeric form of glycolaldehyde, the simplest hydroxyaldehyde. Glycolaldehyde is often supplied as stable dimeric solid, commonly identified as 2,5-dihydroxy-1,4-dioxane.
N,N-Diisopropylethylamine (DIPEA), also known as Hünig’s Base, is a sterically hindered tertiary amine. It is a colorless liquid with a strong amine odor and is widely used as a low nucleophilic organic base in pharmaceutical, agrochemical, and fine chemical synthesis. Due to its bulky structure, DIPEA effectively scavenges acids without participating in unwanted side reactions.
Tris(2,4-di-tert-butylphenyl) phosphite (TDPP) often recognized commercially as Irgafos 168 is a high-performance organophosphorus compound primarily utilized as secondary antioxidant and processing stabilizer. Its characteristic to undergo metallation reaction and provide a cost-effective synthetic processes allows it to be useful in biaryl coupling reactions.
Undecylenic acid is an unsaturated fatty acid naturally derived from castor oil. It is a colorless to pale yellow liquid with antifungal and antimicrobial properties. Chemically known as 10-undecenoic acid, it contains an 11-carbon chain with one double bond and is widely used in pharmaceuticals
5-Nitro Isophthalic Acid (5-NIPA) is an aromatic organic compound derived from isophthalic acid. The presence of two carboxylic acid groups along with a nitro substituent at the 5-position makes it a valuable intermediate in the manufacture of fine chemicals, pharmaceuticals, dyes, pigments, and advanced materials.
Trichloroacetonitrile is a halogenated organic compound belonging to nitrile family. Its strong electrophilic character makes it a valuable intermediate in organic synthesis. It readily undergoes hydrolysis, particularly under acidic or basic conditions, yielding trichloroacetamide and related derivatives.