INTRODUCTION
Calcium Gluconate is the calcium salt of gluconic acid, an oxidation product of glucose, and contains 9.3% calcium, which is about one-third of the calcium in the strength of calcium chloride. It is an ingredient found in a variety of supplements and vitamins and is used to lower potassium in the blood. Calcium gluconate is used as a mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia.
Manufacture
It is made by mixing gluconic acid with calcium carbonate or calcium hydroxide
| Synonyms | Calcium di-(D-gluconate) D-Gluconic acid calcium salt |
| CAS no. | 299-28-5 |
| EINECS no. | 206-075-8 |
| Molecular formula | C12H22CaO14 |
| Molecular weight | 430.37 |
| Structure |  |
Applications
| Calcium gluconate is used to prevent or treat calcium deficiencies. Oral calcium salts are used as dietary supplemental therapy for people who may not get enough calcium in their regular diet |
| Calcium gluconate is used as a cardioprotective agent in high blood potassium |
| Calcium gluconate is the antidote for magnesium sulfate toxicity |
Calcium gluconate is also used as/for:
| Hyperkalemia |
| Hypocalcemia tetany |
| Dietary Supplement |
| Hungry Bone Syndrome |
| Tumor Lysis Syndrome |
SPECIFICATIONS – for injection, EP
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | White or almost white, crystalline or granular powder |
| Solubility | – | Sparingly soluble in water, freely soluble in boiling water |
| Identification A. TLC B. Reaction of Calcium | – – | Shall pass the test Shall pass the test |
| Appearance of solution | – | At 60°C, solution S is not more intensely colored than reference solution B7. After cooling to 20°C, it is not more opalescent than reference suspension II. |
| pH | – | Between 6.4 and 8.3 |
| Organic impurities & Boric acid | – | Shall pass the test |
| Oxalates | ppm | Max 100 |
| Sucrose & reducing sugars | – | No red precipitate is formed |
| Chlorides | ppm | Max 50 |
| Phosphates | ppm | Max 100 |
| Sulphates | ppm | Max 50 |
| Iron | ppm | Max 5 |
| Magnesium & alkali metals | % | Max 0.4 |
| Assay as C12H22CaO14H2O | % | Between 99.0 and 101.0 |
| Microbial Contamination | ||
| Bacterial endotoxins | IU/g | Max 167 |
| Total aerobic microbial count | CFU/g | Max 10(square) |
STORAGE
Store in a cool & dry place. Keep away from moisture.
PACKING
25 kg drum.
REGISTRATION / CERTIFICATION
US-DMF, CEP, EU-GMP, EU-WC (Written Confirmation)
No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Teprenone (Geranylgeranylacetone, GGA) is a mixture of the all-trans and mono-cis isomers of 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one (in a weight ratio of 3:2). It is an acyclic isoprenoid compound with a structure like retinoids and is widely used for the treatment of gastrointestinal ulcers.
Ciclopirox Olamine (CPO) is the N-oxide of a 2 -hydroxy pyridine derivative that carries antifungal, antibacterial, and anti-inflammatory properties. It is composed of 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone combined with 2 aminoethanol (olamine) in a 1:1 ratio.
N,N-Dimethylglycine sodium salt (DMG Na) is the sodium salt form of N,N-dimethylglycine, a tertiary amino acid derivative is white to off white crystalline solid, freely soluble in water.
Blown Castor Oil (15-17 Poise) is a modified grade of Castor oil. The “15-17 Poise” specification refers to its viscosity range, indicating a medium-viscosity blown oil suitable for industrial applications requiring improved body, tackiness, and elasticity compared to regular castor oil.
Dimethylaminoethanol (DMAE) is a is a tertiary amine that is ethanolamine having two N-methyl substituents. It is clear & colourless to pale yellow liquid with ammoniacal odor. DMAE is stable at room temperature and is completely miscible with water as well as organic solvents such as alcohols and ethers. It decomposes at high temperatures. It is a versatile chemical intermediate primarily used as a curing agent for polyurethane foams and epoxy resins.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.
Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.
Methyl-2-Methoxy-5-Sulfamoyl Benzoate (MSMB) is a sulfur containing organic building block acting as a chemical intermediate. MSMB contains ester and sulfamoyl functional groups, which make it useful as a pharmaceutical and fine-chemical intermediate.
Imidazolidinyl urea is a widely used antimicrobial preservative in the cosmetic and personal care industry. It is a formaldehyde-releasing compound that effectively inhibits the growth of bacteria, yeast, and molds, thereby extending the shelf life of formulations. Due to its broad-spectrum efficacy and cost-effectiveness, it is commonly used in rinse-off and leave-on products within regulated concentration limits.