INTRODUCTION
Benzyl nicotinate is a benzyl ester resulting from the condensation of the carboxy group of nicotinic acid with benzyl alcohol.
It has a role as a vasodilator agent and is also generally used in cosmetics and drugs. It is an active substance from the group of rubefacients that stimulates blood circulation. Also used in veterinary as well as in human medicines.
| Synonyms | Nicotinic acid benzyl ester Benzyl pyridine-3-carboxylate |
| CAS no. | 94-44-0 |
| EINECS no. | 202-332-3 |
| Molecular formula | C13H11NO2 |
| Molecular weight | 213.23 |
| Structure |  |
Applications
| Used in the treatment of nutritional deficiencies |
| Used to reduce the plasma cholesterol |
| In combination with heparin, used in the treatment of inflammation of vein (thrombophlebitis), pain in dilated veins area, pains and cramps in the leg muscles, disturbances of lymph circulation, traffic and sports related injuries, postoperative and posttraumatic scars, non-joint rheumatism or soft tissue rheumatism |
| Used as skin-conditioning and anti-static agent in creams, baths and emulsions |
| Used for the synthesis of benzyl palladium complexes to be used as catalysts for the substitution of olefins with benzylic groups |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description | – | Clear, yellowish to brownish yellow or slightly reddish oily liquid with characteristic odor |
| Solubility | – | Miscible with acetone, dichloromethane, ethanol (96%) and in Ether |
| Identification (by IR) | – | Test as per DAB 99 specs should be positive |
| Appearance of solution | – | Test as per DAB 99 specs should comply |
| Acidic substances | – | NMT 1 ml of 0.05 M NaOH solution is consumed |
| Refractive Index | – | 1.569 – 1.570 |
| Halogen Compounds | ppm | NMT 500 |
| Sulphated Ash | % w/w | NMT 0.1 |
| Specific Gravity at 25°C | g/ml | 1.150 – 1.170 |
| Assay (Perchloric acid titration) | % | NLT 98.0 & NMT 101.0 |
| Related Substances (by GC) | ||
| Single impurities | % | NMT 0.5 |
| Total impurities | % | NMT 1.0 |
STORAGE
Store in a cool & dry location and in well-ventilated area.
PACKING
20 kg HDPE Carboy.
Benzyl Nicotinate offered by ExSyn is available on commercial scale. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
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