INTRODUCTION
4-Amino-1,2,4-triazole is an organic solid belonging to the heterocyclic category of compounds. By virtue of presence of 3 nitrogen atoms, the molecule is biologically active and thus acts as antimicrobial and antifungal agent.
Manufacture
It is manufactured by Schmidt reaction in which hydrazine reacts with an aromatic nitrile in aqueous solution to form 4-amino-1,2,4-triazole.
| Synonym | 4H-1,2,4-triazol-4-amine 4-Amino-4H-1,2,4-triazole |
| CAS no. | 584-13-4 |
| EINECS no. | 209-533-5 |
| Molecular formula | C2H4N4 |
| Molecular weight | 84.08 |
| Structure |  |
Applications
| APIs |
|---|
| Carvedilol, an antihypertensive drug |
| Ondansetron, serotonin 5-HT3 receptor antagonist |
| Intermediates |
|---|
| 1-(4-Nitrophenyl)methyl-1,2,4-triazole |
| 4-Amino-1,2,4-triazole HCl |
| 6,8-Dimethyl[1,2,4]triazolo[4,3-b]pyridazine |
| Agrochemicals |
|---|
| Flucanozole, a fungicide |
| Others |
|---|
| Preparation of potent, selective, and orally active cyclooxygenase-2 inhibitor |
| Determination of tryptophan in proteins |
| In FTIR spectroscopy to distinguish between various N atoms based on their vibrational frequencies |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | White to off-white crystalline, hygroscopic powder |
| Solubility | – | Soluble in methanol and water |
| Melting range | °C | 79 – 87 |
| Moisture | % | Max 0.50 |
| Assay (on anhydrous basis) | % w/w | Min 99.00 |
STORAGE
Stored at ambient temperature
PACKING
40 kg HDPE drum
REACH Status
Not registered
ExSyn offers 4-amino-1,2,4-triazole on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
Colchicine is a naturally occurring alkaloid obtained primarily from the autumn crocus (Colchicum autumnale) and related species. It has been used in medicine for centuries, especially for the treatment of gout and Familial Mediterranean Fever. In modern medicine, Colchicine is valued also in conditions like pericarditis, Behçet’s disease, and certain dermatological and cardiac disorders.
1-Butylimidazole is a versatile organic heterocyclic compound belonging to the imidazole family, where a butyl group (–CH₂–CH₂–CH₂–CH₃) is attached to the nitrogen atom at the 1-position of the imidazole ring. Its applications span organic synthesis, materials science, and bioactive compound development due to its tunable physicochemical properties and structural versatility.
Atropine sulfate monohydrate is a chemical compound, specifically a salt of atropine and sulfuric acid, with one water molecule (monohydrate) attached. It is commonly used as a medication and in research due to its anticholinergic properties, meaning it blocks the effects of acetylcholine at muscarinic receptors.
4-Aminobenzoic acid, commonly abbreviated as PABA, is an aromatic amine and carboxylic acid compound. It consists of a benzene ring substituted with an amino group (–NH₂) in the para position to a carboxylic acid group (–COOH).
2-Amino-5-Nitrophenol (5-NAP) is an organic compound with the molecular formula C₆H₆N₂O₃. It is a substituted phenol with both an amino group (-NH₂) and a nitro group (-NO₂) attached to a benzene ring, along with a hydroxyl group (-OH).
Pongamol is a naturally occurring flavonoid primarily extracted from the seeds and leaves of the Pongamia pinnata tree (also known as Karanja tree), native to South and Southeast Asia. It is a cream-colored compound that belongs to the flavonoid family and is known for its antioxidant, anti-inflammatory, antimicrobial, and pesticidal properties. It is one of the key bioactive constituents of Pongamia oil.
Biobased Ethyl Acetate is an environmentally friendly solvent made from renewable sources like bioethanol extracted from sugarcane, corn, and other forms of biomass. Unlike traditional ethyl acetate, which is typically derived from fossil fuels, this green alternative shares the same chemical structure (C₄H₈O₂) and functional performance—offering comparable versatility with a significantly lower environmental footprint.
Palmitoyl chloride is a long-chain fatty acid derivative. It is the acid chloride form of palmitic acid; a saturated fatty acid commonly found in palm oil and other natural fats. It appears as a colorless to pale yellow liquid with a sharp odour and is highly reactive, especially toward water, alcohols, and amines.
Fungal Lycopene is an acyclic carotene belonging to a large group of naturally-occurring pigments known as carotenoids. It contains at least 90% of all-trans-lycopene and minor quantities of 13-cis-lycopene and β- and γ-carotene. It is used as an intermediate in the biosynthetic pathway of β-carotene. Its role in the pharmaceutical and food industries stems from its demonstrated health benefits—such as anticancer and cardiovascular protection—alongside its widespread use as a natural food colorant.