INTRODUCTION
L-Phenylalanine (L-Phe) is an essential and proteinogenic amino acid that helps build proteins and produces brain chemicals like dopamine and norepinephrine. L-Phenylalanine is one of the 20 standard amino acids that form long chains called polypeptides (proteins).The body cannot produce it, so it must be obtained through diet or supplements.
Manufacture
L-Phe is primarily produced through microbial fermentation using genetically engineered bacteria such as E. coli or Corynebacterium glutamicum. The bacteria are cultured in a nutrient-rich medium containing glucose, which they convert into L-Phenylalanine.
| Synonyms | (2S)-2-amino-3-phenylpropanoic acid ; 3-Phenyl-L-alanine; (S)-2-Amino-3-phenylpropionic acid ; H-Phe-OH; L-Phe |
| CAS no. | 63-91-2 |
| EINECS no. | 200-568-1 |
| Molecular formula | C9H11NO2 |
| Molecular weight | 165.19 |
| Structure |  |
Applications
L-Phe is widely used in various fields due to its role as an essential amino acid. It plays a key role in mood regulation, cognitive function, and overall nervous system health.
| Protein Supplement |
| Used in dietary supplements as it’s an essential amino acid needed for protein synthesis |
| Precursor for Neurotransmitters |
| Converts into tyrosine, which is further used to make dopamine, norepinephrine, and epinephrine — important for mood, alertness, and stress response. |
| Food Industry (Aspartame Production) |
| A key ingredient in making L-Aspartame, a low-calorie artificial sweetener. |
| Treatment for Depression and ADHD |
| Sometimes used as a supplement to help manage symptoms. |
| Support in Skin Disorders (e.g., Vitiligo) |
| Studied for its role in melanin production when combined with UV light therapy. |
| Medical Nutrition |
| Included in special medical foods for people with metabolic disorders like PKU (Phenylketonuria) in a very controlled amounts. |
SPECIFICATIONS
| Test | Unit | Specifications |
|---|---|---|
| Appearance | – | White crystals or crystalline powder |
| Identification (By IR) | – | Should conform to the IR absorption of reference standard |
| Residue on ignition | % | NMT 0.4 |
| Chloride (Cl) | % | NMT 0.05 |
| Sulfate (SO4) | % | NMT 0.03 |
| Iron (Fe) | ppm | NMT 30.0 |
| Heavy Metals | ppm | NMT 15.0 |
| Lead (Pb) | ppm | NMT 1.0 |
| Related compounds | ||
| Individual Impurity | % | NMT 0.5 |
| Total Impurities | % | NMT 2.0 |
| Specific rotation (αD25) | ° | -32.7 to -34.7 |
| pH | – | 5.4 – 6.0 |
| Loss on drying | % | NMT 0.30 |
| Total Plate Count | cfu/g | NMT 1000 |
| Assay | % | 98.5 – 101.5 |
STORAGE
Keep container tightly closed in a dry and well-ventilated place.
PACKING
35 Kgs & 50 Kgs HDPE drum.
REACH Status
Not registered
ExSyn offers L-Phenylalanine USP on commercial scales and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
1,4,7-Trimethyl-1,4,7-triazonane (Me₃TACN) is a valuable macrocyclic tridentate ligand derived from 1,4,7-triazacyclononane. In Me₃TACN, each nitrogen atom is substituted with a methyl group, which significantly modifies its steric and electronic properties. Me₃TACN is widely used as a ligand in coordination chemistry due to its ability to form stable complexes with transition metals such as Cu, Ni, Fe, Mn, and Zn.
Adenosine is a naturally occurring purine nucleoside composed of adenine and ribose, present in all living cells. It plays a vital role in biochemical processes such as energy transfer (ATP/ADP), signal transduction, and regulation of physiological functions, and is widely used in pharmaceutical applications.
Methyl-2-Methoxy-5-Sulfamoyl Benzoate (MSMB) is a sulfur containing organic building block acting as a chemical intermediate. MSMB contains ester and sulfamoyl functional groups, which make it useful as a pharmaceutical and fine-chemical intermediate.
Imidazolidinyl urea is a widely used antimicrobial preservative in the cosmetic and personal care industry. It is a formaldehyde-releasing compound that effectively inhibits the growth of bacteria, yeast, and molds, thereby extending the shelf life of formulations. Due to its broad-spectrum efficacy and cost-effectiveness, it is commonly used in rinse-off and leave-on products within regulated concentration limits.
Phosphorodiamidites are a unique class of phosphorus-based compounds characterized by one P–O bond and two P–N moieties. 2-Cyanoethyl tetraisopropylphosphorodiamidite plays a crucial role in solid-phase oligonucleotide synthesis. Beyond their application as synthetic precursors for oligonucleotides, phosphorodiamidites have also been reported as valuable starting materials for the synthesis of industrially relevant polymers and flame-resistant materials, including adhesives, coatings, and laminates.
Ferric maltol is an oral iron complex composed of ferric iron (Fe³⁺) chelated with maltol, designed to improve iron absorption while reducing common gastrointestinal side effects associated with traditional iron salts. It is primarily used in the management of iron deficiency with better tolerability.
Phosphatidylcholine (PC) is one of the most important phospholipids derived from soya lecithin and represents a key structural component of cell membranes. Phosphatidylcholine 90% refers to a highly purified grade where the PC content is enriched to around 90% through specialized extraction and purification steps.
Indorez® Kota Resin is a modified non self-cured phenolic resin, it can increase rubber adhesion to steel, polyester, rayon, nylon, aramid and other fabric cord. It’s an adhesive agent, acts as methylene acceptor, can 100% replace resorcinol and resorcinol resins in resorcinol- formaldehyde-silica, enhance adhesion between rubber and reinforcing materials.
Glyceryl Stearate Citrate (GSC) is a plant-derived, biodegradable emulsifier commonly used in cosmetics and personal-care products. It functions primarily as an anionic oil-in-water (O/W) emulsifier, helping blend oils and water into smooth, stable creams and lotions. Its natural origin and gentle profile make it popular in eco-certified, organic, and sensitive-skin formulations.