INTRODUCTION
2-(Benzylmethylamino)-1-phenylpropanone is an organics intermediate from ketone category. It is a compound with notable pharmacological potential and itself has excellent cytotoxic properties. In trade, the chemicals is referred to as AMK.
Manufacture
2-(Benzylmethylamino)-1-phenylpropanone is manufactured by condensation of N-methyl-benzylamine with bromopropiophenone, the latter is in turn produced from propiophenone.
| Synonym | AMK N-Benzyl-N-methylamino-propiophenone |
| CAS no. | 16735-30-1 |
| EINECS no. | Not available |
| Molecular formula | C17H19NO |
| Molecular weight | 253.34 |
| Structure |  |
Applications
| APIs |
|---|
| Pseudoephedrine HCl |
| Methcathinone |
| Anticancer drugs with more tumor selectivity |
| Intermediates |
|---|
| 1-[4-(2-Aminoethoxyl)phenylcarbonyl]-3,5-bis(benzylidene)-4-piperidone |
| Others |
|---|
| Agrochemicals |
| Material science |
| Building block for novel polymers and ion exchange resins |
| Proteomic research |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Yellowish crystalline powder |
| Identification by IR | – | IR spectrum is concordant with standard |
| Solubility | – | Soluble in chloroform; insoluble in water |
| Melting point | °C | 43.0 – 46.0 |
| Loss on drying | % | Max 3.5 |
| Water | % | Max 3.5 |
| ROI | % | Max 0.2 |
| HPLC Purity | ||
| Propiophenone | % | Max 0.5 |
| Bromopropiophenone | % | Max 0.5 |
| Unspecified impurities | % | Max 0.5 |
| Total impurities | % | Max 1.0 |
| HPLC purity | % | Min 99.0 |
STORAGE
Stored at 2 – 8°C
PACKING
200 kg drum
REACH Status
Not registered
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