INTRODUCTION
Dichloroacetic acid is an organochlorine compound and a corrosive liquid with ammoniacal odor. Its natural occurrence is in seaweeds.
The compound is a versatile chemical reagent. It also possesses medicinal properties and is used as such to treat lactic acidosis, whereby it stems production of lactic acid. It is also employed as a disinfectant.
Manufacture
Dichloroacetic acid is commercially produced as a by-product in chlorination of acetic acid, the main product being chloroacetic acid.
| Synonyms | Bichloroacetic acid 2,2-Dichloroacetic acid |
| CAS no. | 79-43-6 |
| EINECS no. | 201-207-0 |
| Molecular formula | C2H2Cl2O2 |
| Molecular weight | 128.95 |
| Structure | ![]() |
Applications
| Medicinal | As an astringent. Its salts are used as drugs in inhibition of the enzyme Pyruvate Dehydrogenase Kinase. |
| Pharmaceutical | Dichloroacetic acid forms a starting raw material in the manufacture of API Chloramphenicol. |
| Agrochemical | The dihalogenated acid is a key intermediate in production of the herbicide Dichlormid. |
| Other Vital | The compound acts as a detritylation agent in nucleic acid syntheses. It also finds application in peptide production. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Appearance | – | Clear colorless to light yellow liquid |
| Water by KF | % w/w | Max 0.05 |
| Assay by titration | % | Min 99.0 |
| Assay by derivative GC | % | Min 99.0 |
| Impurities by GC: | ||
| 1. Chloroacetic acid | % | Max 1.0 |
| 2. Trichloroacetic acid | % | Max 1.0 |
STORAGE
Product is stored at ambient temperature.
PACKING
40 kg & 250 kg HDPE drums.
ExSyn offers the product on commercial scale and welcomes enquiries. No matter the quantity you need, our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please get in touch with us.
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