INTRODUCTION
Lithium orotate is a compound consisting of lithium, an alkali metal, and orotic acid, a natural substance involved in nucleic acid metabolism. It is a popular dietary supplement due to its potential neuroprotective and mood-stabilizing effects. Unlike lithium carbonate and lithium citrate, which are used in psychiatric medications, lithium orotate is often marketed as a lower-dose alternative for general wellness and mental health support.
MANUFACTURE
The manufacturing process involves a reaction between Lithium hydroxide or Lithium carbonate and Orotic acid to form Lithium orotate. This process ensures the production of a bioavailable lithium salt suitable for pharmaceutical or supplement use.
| Synonyms | Orotic acid lithium salt monohydrate |
| CAS no. | 5266-20-6 |
| EINECS no. | 226-081-4 |
| Molecular formula | LiC₅H₃N₂O₄.H₂O |
| Molecular weight | 180.04 |
| Structure |  |
APPLICATIONS
| Mental Health and Mood Stabilization: |
| Used as a dietary supplement for supporting emotional well-being. |
| Low doses may help with mild anxiety, depression, and mood disorders. |
| Neuroprotection: |
| May support cognitive function and protect brain cells from oxidative stress. |
| Some research suggests it may help in conditions like Alzheimer’s disease and Parkinson’s disease. |
| Bipolar Disorder and Depression: |
| While pharmaceutical lithium is the standard treatment, some people use lithium orotate as an alternative or adjunctive support. |
| Migraine Prevention: |
| Some anecdotal reports and limited studies suggest it may help prevent migraines. |
| Addiction Recovery: |
| Lithium orotate has been explored for its potential role in reducing cravings and withdrawal symptoms in substance abuse recovery. |
SPECIFICATIONS
| Test | Unit | Specification |
|---|---|---|
| Description | – | White fine powder |
| Solubility | – | Slightly soluble in water |
| Identification | ||
| A. Positive for Lithium B. IR | – – | Should comply Should comply with structure |
| Lead | ppm | Max 1.0 |
| Arsenic | ppm | Max 5.0 |
| Mercury | ppm | Max 1.0 |
| Loss on drying | % | Max 5.0 |
| Li content (on anhydrous basis) | % | 4.0 – 4.4 |
| Microbial parameters: | ||
| Total Plate Count | per gm | Max 3000 |
| Yeast & Mould | per gm | Max 300 |
| Salmonella | – | Should be negative |
| Staphylococcus Aureus | – | Should be negative |
| Coliform | – | Should be negative |
| E. Coli | – | Should be negative |
PACKING
25 kg or 50 kg bag/drum
STORAGE
Store in airtight container in a cool, dry place
REACH status
Not registered
ExSyn offers Lithium orotate on commercial scales and welcomes enquiries. Our exceptional quality and service will make ExSyn your supplier of choice! If you need any additional information or SDS, please contact us.
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